Friday, April 3, 2015

Cerebrospinal Fluid, Autoimmunity, and Cognitive Dysfunction in ME/CFS

The hippocampus, a small organ located in the limbic
system, is associated with short-term memory, learning
 and spatial navigation. 
Columbia University has published the second of two significant studies examining immune system markers in ME/CFS. The study, "Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome," was published in Molecular Psychiatry, a top-ranked journal in the field of neuroscience.

The first study, "Distinct plasma immune signatures in ME/CFS are present early in the course of illness" (February 27, 2015), showed that pro-inflammatory cytokines were elevated in the early phase of the disease, but depressed in later stages. After examining cerebrospinal fluid in long-term patients, the Columbia research team found a similar decrease in pro-inflammatory cytokine IL-1 signaling.

What is interesting about the cerebrospinal fluid study is that patients showed an increase in a chemokine called CCL11 (eotaxin).

Eotaxin is a chemical involved in stimulating eosinophils, immune molecules that are implicated in allergic responses. Studies have shown that increased eotaxin reduces cognitive performance. Particularly affected are spatial navigation and the processing of short into long-term memory (learning). These are both functions of the hippocampus, a small organ in the limbic system.

In his book, The Limbic Hypothesis (1993), Dr. Jay Goldstein proposed the damage to the limbic system was the driving force behind ME/CFS. Research conducted since then has repeatedly confirmed Dr. Goldstein's theory. Now, evidence is mounting that the damage is caused by an autoimmune response.

The Columbia researchers concluded that their results:
"...indicate a markedly disturbed immune signature in the cerebrospinal fluid of cases that is consistent with immune activation in the central nervous system, and a shift toward an allergic or T helper type-2 pattern associated with autoimmunity."
_________________________________ 

Scientists find clues into cognitive dysfunction in chronic fatigue syndrome

Press Release: Columbia University's Mailman School of Public Health, March 31, 2015. Scientists at Columbia University's Mailman School of Public Health have identified a unique pattern of immune molecules in the cerebrospinal fluid of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) that provides insights into the basis for cognitive dysfunction - frequently described by patients as "brain fog" - as well as new hope for improvements in diagnosis and treatment.

In the study published in Molecular Psychiatry, Mady Hornig, MD, and colleagues used immunoassay testing methods to measure the levels of 51 immune biomarkers called cytokines in the cerebrospinal fluid of 32 people with ME/CFS for an average of seven years, 40 with multiple sclerosis, and 19 non-diseased controls. The researchers found that levels of most cytokines, including the inflammatory immune molecule, interleukin 1, were depressed in individuals with ME/CFS compared with the other two groups, matching what was seen in the blood study in patients who had the disease for more than three years. One cytokine - eotaxin - was elevated in the ME/CFS and MS groups, but not in the control group.

"We now know that the same changes to the immune system that we recently reported in the blood of people with ME/CFS with long-standing disease are also present in the central nervous system," says Dr. Hornig, professor of Epidemiology and director of translational research at the Center for Infection and Immunity at the Mailman School. "These immune findings may contribute to symptoms in both the peripheral parts of the body and the brain, from muscle weakness to brain fog."

Implications for Diagnosis and Treatment

"Diagnosis of ME/CFS is now based on clinical criteria. Our findings offer the hope of objective diagnostic tests for disease as well as the potential for therapies that correct the imbalance in cytokine levels seen in people with ME/CFS at different stages of their disease," adds W. Ian Lipkin, MD, John Snow Professor of Epidemiology and director of the Center for Infection and Immunity. There is precedent for use of human monoclonal antibodies that regulate the immune response in a wide range of disorders from rheumatoid arthritis to multiple sclerosis. However, the researchers note, additional work will be needed to assess the safety and efficacy of this approach.

Journal Reference: M Hornig, G Gottschalk, D L Peterson, K K Knox, A F Schultz, M L Eddy, X Che, W I Lipkin. Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome. Molecular Psychiatry, 2015; DOI:10.1038/mp.2015.29

32 comments:

  1. Every bit of good news is always welcome. Thanks for writing your blog - always a great read!

    ReplyDelete
    Replies
    1. I NEED A GENUINE SPELL CASTER TO BRING BACK MY EX BACK: CONTACT DOCTOR THOUGH HIS WEB SITE https://ultimatespellcast3.wixsite.com/dr-trust HE IS THE BEST OF ALL

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    2. HOW TO GET EX BACK.
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  2. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  3. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  4. .,AM from United states .i never believed in love spells or magic until i met this spell caster once when i went to Africa in June last year on a business summit i meet a man called Dr oku, is powerful he could help you cast a spells to bring back my love s gone misbehaving lover looking for some one to love you bring back lost money and magic money spell or spell for a good job i m now happy & a living testimony cos the man i had wanted to marry left me 4weeks before our wedding and my life was upside down cos our relationship has been on for 3 year i really loved him, but his mother was against me and he had no good paying job so when i met this spell caster, i told him what happened and explained the situation of things to him at first i was undecided,skeptical and doubtful, but i just gave it a try and in 6 days when i returned to taxes my boyfriend (is now my husband ) he called me by himself and came to me apologizing that everything had been settled with his mom and family and he got a new job interview so we should get married i didn't believe it cos the spell caster only asked for my name and my boyfriends name and all i wanted him to do well we are happily married now and we are expecting our little kid and my husband also got a new job and our lives became much better in case anyone needs the spell caster for some help his email address: okutemple@gmail.com call him or add him on whats-app +2347053113465

    ReplyDelete
  5. I lost my 1 years relationship three months ago . My ex left me with so many pains and since then I have been heart broken and shattered. I have contact 11 spell casters and 8 of them has rip me off my money without any result. I have Emailed so many sites online looking for a good spell caster till I was directed by a 28 years old girl to DR ADODA who help. At first I never believed him because he was requesting for some amount of money to buy items, it took him three weeks to convince me and something occur to my mind and I said let me give him a try . I was very shocked when Marcus called three days after I sent Dr ADODA HELP the items money. He apologies for all he has done wrong and I am very happy that we are together today because he proposed to me last night that we are getting married next month. I will advise you to contact Email :adodalovespelltemple@gmail.com. because he has done wonders in my life and I believe he can help you out in any problem. FROM MISS Arabella.....

    ReplyDelete
  6. I lost my 1 years relationship three months ago . My ex left me with so many pains and since then I have been heart broken and shattered. I have contact 11 spell casters and 8 of them has rip me off my money without any result. I have Emailed so many sites online looking for a good spell caster till I was directed by a 28 years old girl to DR ADODA who help. At first I never believed him because he was requesting for some amount of money to buy items, it took him three weeks to convince me and something occur to my mind and I said let me give him a try . I was very shocked when Marcus called three days after I sent Dr ADODA HELP the items money. He apologies for all he has done wrong and I am very happy that we are together today because he proposed to me last night that we are getting married next month. I will advise you to contact Email :adodalovespelltemple@gmail.com. because he has done wonders in my life and I believe he can help you out in any problem. FROM MISS Arabella.....

    ReplyDelete
  7. Today has being the most happiest day of my life after 1 year of sadness and sorrow without being with the one i love, i tried all my possible best to make sure i make my lover happy but it never seems to work out well it was like am doing everything in vain but all thanks to Dr Ogudugu for coming to change all my worries and sadness to Joy. I knew the great man when i read some wonderful reviews about Him how he has helped a lots of people on there relationship problem i was reading a magazine which then i saw great testimonies as well which then i decided not to waste time. He told me not to worry that he assures me that within 48 hours everything would be sorted out i believed Dr Ogudugu so much because i believe he can't fail me and i sent him all my details. Truly Dr Ogudugu never failed me,my husband who left me for good a year come back to me. My husband and i have been living contentedly since this spell caster reunited us together with his love spells. Thank you so so so much Dr Ogudugu for your powerful spells. Expressions are not sufficient to say thank you, here is his email address GREATOGUDUGU@GMAIL.COM he can be of help to you on any problem like
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    ReplyDelete
  8. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  9. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  10. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him... Email: okutemple@gmail.com or add him on whasapp +2347053113465

    ReplyDelete
  11. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him... Email: okutemple@gmail.com or add him on whasapp +2347053113465

    ReplyDelete
  12. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him. Email: okutemple@gmail.com or add him on whasapp +2347053113465

    ReplyDelete

  13. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  14. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  15. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him. Email: okutemple@gmail.com or add him on whasapp +2347053113465

    ReplyDelete
  16. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him. Email: okutemple@gmail.com or add him on whasapp +2347053113465

    ReplyDelete
  17. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  18. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  19. I am Jessica by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this great spell caster on this email address azaspellcaster@gmail.com ,have help a woman to get back her husband, i emailed him too and he told me that a woman had a spell on my husband and he told me that he will help me and after 24 hours that i will have my husband back. i believed him because i have no other choice and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now. happy with my husband. Thanks to Dr Aza. His email: azaspellcaster@gmail.com or whatsApp him on his telephone number +2348107155060 you can contact him on his web http://azaspellcaster.wixsite.com/spell-caster

    ReplyDelete
  20. BE CAREFUL HERE MANY OF THE DOCTORS HERE ARE SCAM,MOST TESTIMONIES OF MOST SPELL CASTER HERE MUST BE IGNORE.BECAUSE THEY ARE SCAM I MEAN REAL SCAM WHICH I WAS A VICTIM.I GOT RIPPED OF THREE THOUSANDS DOLLARS BY 4 CASTERS BECAUSE I WAS SO ANXIOUS TO GET MY WIFE BACK AFTER SHE LEFT ME FOR ALMOST 2 YEARS WITH OUR 4 YEARS OLD SON JERRY,, I HAVE PAID OVER $3000 ON SPELL CASTING AND COURIER AND NOTHING HAVE WORK FOR ME UNTIL ONE FAITHFUL DAY I GOT IN CONTACT WITH MADAM SOLUTION WHO DID WHAT I CALLED MAGIC BECAUSE I CONTACTED HER ON FRIDAY AND AFTER GIVEN HER MY DETAILS AND $245 FOR THE SPELL CASTING MY WIFE CALLED ME ON SUNDAY AND NOW WE ARE BACK TOGETHER AGAIN IF YOU NEED SIMILAR HELP THEN CONTACT HER NOW VIA EMAIL AT (magic.lovespel@reincarnate.com) .

    ReplyDelete
  21. I feel so blessed again in my marriage after Doctor Oku brought back my husband that separated with me for good 3 mounths. Am Jessica Butler by name from USA. Even though i have mouths all over my body, it won't be enough to thank Doctor Oku for his help upon my life. My husband separated with me for the 3 months and have been in pains and agony without him. So, i searched for help everywhere but nothing worked out not until i meant Doctor Oku who i contacted online. I explained my situation to him and he promised that my husband will get back to me within 24 to 48 hours as far that my heart still beats for him. I believed in him and he prepared a spell for me and my husband called me exactly when Doctor Oku said. He pleaded and said he needs me back and now we are living happily again for the past 9 months. Everyone out there reading my article that needs help should contact him... Email: okutemple@gmail.com or call +2347053113465

    ReplyDelete
  22. My name is Kesby Karen i am very happy for the wonderful work Dr bolingo has done for me i got married to my lovely husband last year February and we have a lovely son. things was going well with us and we are living happily. until one day my husband started behaving in a strange manner i could not understand, i was very confused with the way he treat me and my son. later that month he did not come home again and he called me that he want a divorce, i asked him what have i done wrong to deserve this from him, all he was saying is that he want a divorce that he hate me and do not want to see me again in his life, i was sad and also frustrated i did not know what to do,i was sick for more than a week because of the divorce. i love him so much he his everything to me without him my life is incomplete. i told one of my child hood friend and she told me to contact a spell caster that she has listen to one woman who testify about dr bolingo and she has been hearing about him that i should try him i never believe in all this spell casting of a thing but i just say i should try if something will come out of it. i contacted Dr bolingo for the return of my husband to me, he told me that my husband have been taken by another woman. that she cast a spell on him that is why he hate me and also want to divorce me. then he told me that has to cast a spell on him that will make him return to me and my son, he casted the spell and after 1 day my husband came back home and started apologizing he said that he love me so much that he did not know what happen to him that he left me. it was the spell that Dr bolingo casted on him that make him come back to me,right now am so happy again. thank you Dr bolingo for what you have done for me i would have been nothing today if not for your great spell. this is to every one who is facing divorces or heart break by your lover i want you to contact him now because he can do it for you his powers is great and dont have any side effect in the future contact him through his mail: bolingospelltemple@gmail.com or call him on his cell phone number +2348071169835 contact him now and your problems will be solve for ever.once again thanks to dr bolingo.

    ReplyDelete
  23. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  24. How I Got My Ex Husband Back...........

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

    ReplyDelete
  25. Read Up My Story Today as my story is a very special and unique one as is not like the numerous advert you always see online and also I want to be 100% sincere and truthful to you that there can never be any other online spell caster that can help you bring back your EX BACK to you other than DR OTIS DARKO as he alone is 100% effective,dynamic and very reliable as 99.9% of other spell casters are not for real and can never help you solve your problems at all instead they will complicate your present condition OK SO BE WISE AND ALSO BE WARNED AND CONTACT DR OTIS DARKO TODAY... MY OWN LIFE STORY / EXPERIENCES IS BELOW:


    My Name is Alan Pratte, From USA. I wish to share my testimonies with the general public about what this man called Dr OTIS DARKO has just done for me , this man has just brought back my lost Ex WIFE to me with his great spell, I was married to this woman called Sharon we were together for a long time and we loved our self’s but when I was unable to make her pregnant for me and also give her al she needs she left me and told me she can’t continue anymore then I was now looking for ways to get her back until a friend of mine told me about this man and gave his contact email: otisdarko60@yahoo.com then you won't believe this when I contacted this man on my problems he prepared this spell cast and bring my lost WIFE back, and after a month she became pregnant for me because he gave me some herbs to take also and when she went for a test and the result stated that she was pregnant am happy today am a FATHER of a baby girl, thank you once again the great DR OTIS DARKO for what you have done for me, if you are out there passing through any of this problems listed below:

    (1) If you want your ex back.
    (2) if you always have bad dreams.
    (3) You want to be promoted in your office.
    (4) You want women/men to run after you.
    (5) If you want a child/PREGNANCY SPELL.
    (6) You want to be rich.
    (7) You want to tie your husband/wife to be
    yours forever.
    (8) If you need financial assistance.
    (9) How you been scammed and you want to recover you lost money.
    (10)Stop Divorce
    (11) CURE TO ALL KIND OF SICKNESS/DISEASES HERE
    (12) Winning of lottery
    (13) Cure To Hiv/Aids
    (14) LOTTERY/LOTTO SPELL WINNING
    (15) CURE TO HERPES AND ANY OTHER SEXUALLY TRANSMITTED DISEASES AT ALL...
    (16) HAVE YOU BEEN SCAMMED BEFORE AND NEEDS TO RECOVER ALL THE DOLLARS/MONEY YOU LOST TO THESE FRAUDSTER ???.. CONTACT OTIS DARKO AS HE HELPED MY FRIEND CALLED LEONARD CAPTAIN FROM USA TO RECOVER BACK THE SUM OF $300,000.00 DOLLARS HE LOST TO SCAMMERS ONLINE

    Email... otisdarko60@yahoo.com...... YOU CAN ALSO ADD HIM UP ON WHATSAPP USING THIS MOBILE NUMBER:+2348077526136

    ReplyDelete
  26. I NEED A GENUINE SPELL CASTER TO BRING BACK MY EX BACK: CONTACT DOCTOR THOUGH HIS WEB SITE https://ultimatespellcast3.wixsite.com/dr-trust HE IS THE BEST OF ALL

    It's a privilege to share this miraculous testimony to the world. I'm Elisa Wendy from England. My husband divorced me 4 months back and i have been filled with remorse for i didn't know what to do to amend issues with my husband. I searched for help on the internet on how i could get help in my marriage and i discovered great testifiers about Doctor Trust who has been progressive with his spells. I got in touch with him and behold, Doctor Trust told me that he will prepare a spell for me that will bring back my husband. I was skeptical but i had no other option but to work with him. 2 days after, my husband called me that he's coming back home and from that day till this moment, we have been living peacefully. He is back now with so much love and caring. today i am glad to let you all know that this spell caster have the powers of bring lovers back. because i am now happy with my husband,and the most surprise,is that our love is very strong,every day is happiness and joy. and there is nothing like been with the man you love. I will highly recommend Doctor Trust to anyone one out there who needs help whatsoever.if you have any problem contact Doctor Trust, i give you 100% guarantee that he will help you!!.

    Ultimatespellcast@gmail.com or Ultimatespellcast@yahoo.com
    Call or write him on What-app +2348156885231

    ReplyDelete
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    ReplyDelete
  28. ATTENTION TO THE WHOLE WORLD:

    Hello and blessed are you who found me. My name is DR OTIS DARKO ( otisdarko60@yahoo.com ), and am here to help you change and transform your life in the most positive way possible. I use the power of white, black craft and Wicca and voodoo spell casting to help people just like you they get the love they want and the money they deserve.


    My love spell offer amazing and quick results. Do you want to find your soulmate? Do you want to reunite with a past lover and make him or her love you again? Do you need to bind a troublemaker from causing problems in your relationship? With my spell casting service, I can cast a love spell on your behalf that will help all of your wishes and dreams come true. I also do other custom spells, such as money spells, job spells, friendship spells, and good luck spells.


    You may have already tried the power of spells and prayers to get what you want. Although it is true that everyone has the ability to cast spells and perform magic, spell casting is like a muscle. Everyone has this 'muscle' but the more you use it, the stronger it gets, and the more things you are able to do with it. If you are not an experienced spell caster, your spell may not be as strong, and the results not as quick as you may desire. GET YOUR PROBLEMS SOLVE HERE AND BE FREE!!

    Hello to people that want to be Great,

    Note: This Spell casting do not have any effect on any one, But just to get your problem solve ok.
    Get your problem solve in master...You can get the bellow problems solve here.

    1. Bring back lost lover, even if lost for a long
    time
    2. Remove bad spells from homes, business
    & customer attraction etc.
    3. Get promotion you have desired for a long time at work or in your career.
    4. Remove the black pot that keeps on taking your money away
    5. Find out why you are not progressing in life and the solution
    6. Eliminate in family fights
    7. Ensure excellent school grades even for children with mental disabilities
    8. Stop your marriage or relationship from
    breaking apart
    9. I destroy and can send back the Nikolos if requested
    10. We heal barrenness in women and disturbing menstruation
    11. Get you marriage to the lover of your choice
    12. Guarantee you win the troubling court cases & divorce no matter how what stage
    13. Ensure success in work and business
    14. Mental illness & bewitched
    15. Can’t sleep at night or walking at night
    16. Recover stolen property and
    whereabouts of people that hurt you.
    17. Bring supernatural luck into your home
    18. Extreme protection for those doing dangerous jobs like security guards, Bank manager, cash transporters, etc

    I have over 20 years of spell casting experience, and i have successfully cast spells to help hundreds of people improve their love life, financial situation, and happiness.

    I can help you, and I want to help you. Read through my words and CONTACT ME VIA: otisdarko60@yahoo.com AS MY POWERS ARE SO STRONG AND VERY EFFECTIVE AND HAS NO BAD EFFECT INSTEAD IT HAVE A VERY GOOD RESULT AFTER CASTING THE SPELL. CONTACT HIM AGAIN ON HIS EMAIL ADDRESS: otisdarko60@yahoo.com............. YOU CAN ALSO ADD HIM UP ON WHATSAPP USING THIS MOBILE NUMBER:+2348077526136

    ReplyDelete
  29. HOW TO GET EX BACK.
    I have something to share with you!!! There is a great joy in my heart which I want to share with everyone. My name is Isabel Martins . I had a misunderstanding with my lover several months ago; which led us to break up and he never wanted to hear my voice again. But as time went on, a good friend of mine recommended DR PEPOKO who could help me with Love Spell to get my man back. At first, I thought the idea of a love spell was strange,but was willing to give it a try because i really love my boyfriend. For the first time I was scared to contact the DR PEPOKO because I was not sure if what they did was against my religion. But my friend assured me that they only use Spell which is safe and has no side effects. I felt a little better and decided to contact DR PEPOKO on his mail (pepokolovespell@gmail.com)I contacted him through his email and explained everything to him. He said that I shouldn't worry, that my lover will come back to me on his knees begging for forgiveness. I bought an item that he told me to buy for the preparation of the spell and assured me that my lover will come to me within 48 hours in remorse. My greatest joy now is that he actually came back to me and fell on his knees begging for forgiveness. We got back together and our relationship has been better this second time around. I have to give DR PEPOKO all the credit for helping us get back to a better place than where we began. The new found love that my boyfriend has for me is incredible and i can't wait to see what the future holds for us. Do you have any problem with your loved one? Well worry no more because DR PEPOKO can provide you with a spell to get him or her back. With the help of a spell just as he helped me. Contact DR PEPOKO via email: pepokolovespell@gmail.com
    or visit he Website www.pepokolovespelltemple.blogspot.com
    Here is my details also if you wish to contact me personal::: isabel_martins28@outlook.com

    ReplyDelete
  30. TAKE IT OR LEAVE WE STILL REMAIN THE ONLY TRUE EXISTING SPELL CASTER ON EARTH.
    Warm Regards to all that has lost there job, lost there lovers, the ones that are battling with examination to pass, you need to win a lotto, you need to do death spell for your enemy, you want to get what your heart desire without working nor doing anything to get it, With the help of Dr Ajayi Ololo, Theses problems are solved.. Cos over here in this great temple that is know world wide as the best and greatest spell caster temple, There is no problem that do not have a solution when you come to this temple OF OLOLO. I will also want all of you to know that there are so many swindlers / scammers that has claim to be spell caster, Just to get money from those that need help. I also come to tell you to beware of these so called temples online that can never help you solve your problem. I Dr Ajayi Ololo will want to tell you all that there iS no spell caster online that can ever be like us, Cos we have helped so many individuals to get all there heart desire online. Anyone that require the help of our services should kindly send an email to the following email address: ajayiololo@yahoo.com .

    ReplyDelete

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